| Article Title: |
Genetic modification of plants: significant issues and
hurdles to success. |
| Article Source: |
Am J Clin Nutr 1996 Apr;63(4):651S-6S |
| Author(s): |
Day PR |
| Abstract: |
Transformation and regeneration is routine for many crop
plants. A genetically engineered tomato with a longer shelf life at full
ripeness was introduced in the United States in 1994, and other soon-to-be-released
products, both foods and fibers, incorporate genes for resistance
to pests, diseases, and environmentally benign herbicides. Other possibilities
are altered plant fats and oils, methionine- and lysine-enhanced grain
and legume proteins, plant foods that can deliver
immunizing antigens, and other ways of controlling fruit
ripening. Food safety concerns include the inadvertent production
of toxicants and allergens. Foreign DNA can be introduced into plants
by bacterial vectors, direct uptake by protoplasts, and mechanical introduction
on metal particles or other materials. Limitations include little or no
control of copy number or site of integration of the introduced DNA, dependence
on selectable markers for recovery of traits, and inadequate knowledge
of how to control key metabolic steps to maximize desirable traits. Directed
genetic change still requires conventional crop breeding to deliver benefits
to farmers and consumers. |
| Author's Address: |
Center for Agricultural Molecular Biology, Rutgers, The
State University of New Jersey, New Brunswick, 08902, U.S.A. |
| Major Subject Heading(s): |
Genetic Engineering; Plants, Transgenic |
| Minor Subject Heading(s): |
6-Phytase [biosynthesis] |
| Minor Subject Heading(s): |
6-Phytase [biosynthesis] [genetics]; Food Hypersensitivity
[prevention & control]; Herbicides [toxicity]; Metalloproteins [biosynthesis]
[genetics]; Pest Control, Biological; Plant Oils [chemistry]; Plant Proteins
[biosynthesis] [chemistry] [genetics]; Plant Viruses [genetics] [immunology];
Plants [growth & development] [physiology]; Rice [adverse effects]
[genetics]; Transformation, Genetic |
| Unique NLM Identifier: |
96181062 |
Indexing Check Tags: |
Animal; Human; Support, Non-U.S. Gov't |
| Publication Type: |
JOURNAL ARTICLE; REVIEW (34 references); REVIEW, TUTORIAL |
MEDLINE Indexing Date: |
9606 |
| ISSN: |
0002-9165 |
Language: |
English |
CAS Registry/
EC Numbers: |
EC 3.1.3.26 (6-Phytase); 0 (Herbicides); 0 (Metalloproteins);
0 (Plant Oils); 0 (Plant Proteins); 98726-08-0 (phytochelatin) |
